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pentobarbital will minimize the level or impact of cinacalcet by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.Contraindicated (1)pentobarbital decreases levels of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Powerful CYP3A4 inducers can lessen panobinostat ranges by ~70% and bri